Ralf Schmidmaier Selected Research

LFA 878

10/2007

Inhibition of lymphocyte function associated antigen 1 by LFA878 induces apoptosis in multiple myeloma cells and is associated with downregulation of the focal adhesion kinase/phosphatidylinositol 3 kinase/Akt pathway.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ralf Schmidmaier Research Topics

Disease

21	Multiple Myeloma 11/2016 - 09/2003
5	Cushing Syndrome 05/2021 - 06/2017
4	Neoplasms (Cancer) 01/2020 - 04/2015
3	Muscular Diseases (Myopathy) 05/2021 - 06/2017
2	Bone Resorption 01/2021 - 01/2020
2	Sarcopenia 01/2021 - 01/2019
2	Somatoform Disorders (Somatoform Disorder) 02/2019 - 01/2007
2	Infections 09/2011 - 02/2004
1	Parkinson Disease (Parkinson's Disease) 06/2022
1	Dementia (Dementias) 06/2022
1	Multiple Sclerosis 06/2022
1	Parathyroid Neoplasms (Parathyroid Neoplasm) 05/2022
1	Primary Hyperparathyroidism 05/2022
1	Muscular Atrophy (Muscle Atrophy) 05/2021
1	Hypophosphatemia 01/2020
1	Oncogenic osteomalacia 01/2020
1	Endometrial Neoplasms (Endometrial Cancer) 01/2020
1	Wounds and Injuries (Trauma) 04/2019
1	Mental Disorders (Mental Disorder) 02/2019
1	Inflammation (Inflammations) 09/2017
1	Obesity 09/2017
1	Osteoporosis 06/2017
1	Pneumonia (Pneumonitis) 04/2015
1	Hodgkin Disease (Hodgkin's Disease) 11/2012
1	Bisphosphonate-Associated Osteonecrosis of the Jaw 01/2012
1	Subcutaneous panniculitis-like T-cell lymphoma 09/2011
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 09/2011
1	Neutropenia 09/2011
1	Connective Tissue Diseases (Connective Tissue Disease) 01/2011
1	Body Weight (Weight, Body) 03/2009
1	Rheumatoid Arthritis 02/2009

Drug/Important Bio-Agent (IBA)

4	GlucocorticoidsIBA 05/2021 - 06/2017
3	TOR Serine-Threonine KinasesIBA 04/2015 - 02/2009
3	Melphalan (Alkeran)FDA LinkGeneric 09/2011 - 09/2004
3	treosulfanIBA 09/2004 - 09/2003
2	Insulin-Like Growth Factor I (IGF-1)IBA 05/2021 - 01/2021
2	CytokinesIBA 02/2019 - 07/2008
2	Proteins (Proteins, Gene)FDA Link 06/2017 - 09/2004
2	Everolimus FDA Link 04/2015 - 04/2009
2	Pharmaceutical PreparationsIBA 04/2015 - 02/2009
2	Histone Deacetylases (Histone Deacetylase)IBA 03/2012 - 05/2010
2	Histone Deacetylase InhibitorsIBA 03/2012 - 05/2010
2	Phosphotransferases (Kinase)IBA 01/2012 - 04/2009
2	Adenosine Monophosphate (AMP)IBA 10/2007 - 04/2007
2	Protein Kinases (Protein Kinase)IBA 10/2007 - 04/2007
2	Simvastatin (Zocor)FDA LinkGeneric 09/2007 - 09/2004
1	Choline (Choline Chloride)IBA 05/2022
1	fluorocholineIBA 05/2022
1	Insulin-Like Growth Factor Binding ProteinsIBA 05/2021
1	Insulin-Like Growth Factor Binding Protein 3IBA 05/2021
1	AlbuminsIBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2020
1	Parathyroid Hormone (Parathormone)IBA 01/2020
1	Alkaline PhosphataseIBA 01/2020
1	Fibroblast Growth Factor-23IBA 01/2020
1	Tartrate-Resistant Acid PhosphataseIBA 01/2020
1	Cisplatin (Platino)FDA LinkGeneric 01/2020
1	GlycolipidsIBA 01/2020
1	OsteocalcinIBA 01/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 02/2019
1	Tryptophan (L-Tryptophan)FDA Link 02/2019
1	KynurenineIBA 02/2019
1	Biomarkers (Surrogate Marker)IBA 09/2017
1	Glucose (Dextrose)FDA LinkGeneric 09/2017
1	C-Reactive ProteinIBA 09/2017
1	Imatinib Mesylate (Gleevec)FDA Link 01/2016
1	CR2408IBA 03/2012
1	8- (6- methoxypyridin- 3- yl)- 3- methyl- 1- (4- piperazin- 1- yl- 3- trifluoromethylphenyl)- 1,3- dihydroimidazo(4,5- c)quinolin- 2- oneIBA 01/2012
1	Diphosphonates (Bisphosphonates)IBA 01/2012
1	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2011
1	AutoantibodiesIBA 01/2011
1	resminostatIBA 05/2010
1	NF-kappa B (NF-kB)IBA 02/2010
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2010
1	NVP-AEW541IBA 04/2009
1	EnzymesIBA 03/2009
1	CreatinineIBA 03/2009
1	Peptides (Polypeptides)IBA 03/2009
1	SemicarbazonesIBA 03/2009
1	Proteasome InhibitorsIBA 03/2009
1	(1- (1- ((2,4- dioxoimidazolidin- 1- ylimino)methyl)- 2- phenylethylcarbamoyl)- 2- (1H- indol- 3- yl)ethylcarbamoyl)- 2- (1H- indole)IBA 03/2009
1	teriflunomideIBA 02/2009
1	Dihydroorotate DehydrogenaseIBA 02/2009
1	Propidium (Propidium Iodide)IBA 02/2009
1	Conditioned Culture MediaIBA 02/2009
1	FITC-annexin A5IBA 02/2009
1	Bromodeoxyuridine (BrdU)IBA 02/2009

Therapy/Procedure

12	Therapeutics 01/2019 - 02/2004
5	Drug Therapy (Chemotherapy) 01/2020 - 02/2004
3	Stem Cell Transplantation 01/2012 - 02/2004
1	Oral Hygiene (Dental Hygiene) 06/2022
1	Parathyroidectomy 05/2022
1	Activities of Daily Living (ADL) 01/2021
1	Vertebroplasty 04/2019
1	Polypharmacy 09/2017
1	Length of Stay 06/2017
1	Induction Chemotherapy 11/2016
1	Autologous Transplantation 11/2016